Sheng Gong currently works at the Department of Materials Science & Engineering, Massachusetts Institute of Technology. He is also a professor of neuroscience in MITs Department of Brain and Cognitive Sciences, and an affiliate of both The Picower Institute for Learning and Memory and the McGovern Institute for Brain Research. Key scientific datasets and computational tools developed by our scientists and their collaborators. Our group aims to redesign existing proteins and engineer new proteins that overcome these limitations. My research will involve a combination of organic synthesis, microbiology, molecular biology, enzymology, and potential optimization of . The Gerstner Center is developing next-generation diagnostic technology for cancer detection and tracking disease progression. Broad Institute 4.0. The Elowitz lab is committed to creating an inclusive, diverse, and supportive environment, and we encourage postdoc applications from groups historically under-represented in science. fayetteville state basketball; Tags . Long-Sheng Chang, PhD. Access free classroom materials and more for STEM educators, parents, students, tutors, and others. Distinguished Investigator and Professor at Gladstone Institute of Cardiovascular Disease, and Department of Pharmaceutical Chemistry, University of California San Francisco. Learn about Broad Institute's mentored research offerings for high school students, college students, and recent college graduates. Abudayyeh-Gootenberg lab, McGovern Institute, and Zhang lab, McGovern Institute/Broad Institute Gloria Choi Image credit: Justin Knight/McGovern Institute. I am currently an Associate Computational Biologist II in the Morgan Sheng lab at the Broad Institute of MIT and Harvard. Dr. Sheng was elected to AAAS Fellow in 2016 and ASCB fellow in 2017 for his contributions to the field of axonal transport of mitochondria and endolysosomes in maintenance of neuronal homeostasis and synaptic function in health and diseases. Requests for exemption for medical or sincerely held religious beliefs will be considered. Fralin Biomedical Research Institute faculty conduct research in wet and dry labs in our 280,000-square-foot facilities . Merkin Building USA. Morgan Sheng, a neurobiologist and physician-scientist with deep experience in both basic research and drug discovery, has joined the Broad Institute of MIT and Harvard as its newest Core Member and as Co-Director of the institute's Stanley Center for Psychiatric Research.He will also return to MIT, after a decade in industry, as a professor of neuroscience in the Department of Brain and . . We are a team of scientists studying the genetic basis and molecular mechanisms underlying schizophrenia and other brain disorders. Postdoctoral Fellow, Laboratory of Steven McCarroll, Harvard Medical School and Broad Institute of MIT and Harvard. In November 2022, Broads Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th. Developing a resistant cultivar and inducing plant defenses by elicitor application are currently two of the best options to control this disease. The repertoire of naturally occurring proteins is limited and many molecules induce multiple conflicting effects. He joined NINDS as an investigator in 1997 and is now a tenured senior investigator . 1 Broad Institute of MIT and . Raozhou Lin is a molecular neuroscientist with a keen interest in understanding the causes for neuropsychiatric diseases. Gladstone-UCSF Institute of Genomic Immunology . A catalog of scientific papers published by our members and staff scientists. Yeh FL, Wang Y, Tom I, Gonzalez LC, Sheng M. Neuron 2016 Jul 20;91(2):328-40. This study aimed to uncover and analyze the mitophagy-related diagnostic biomarkers in HCC using . The inflammatory targets include cyclooxygenase-1 (COX-1), COX-2, and translocator protein (TSPO) and are studied in comparison to beta-amyloid and tau protein. A catalog of scientific papers published by our members and staff scientists. 2018 Dec 19;100(6):1322-1336.e7. However, it is extremely difficult to realize at the single-molecule level. The successful candidate will join a multidisciplinary group and perform cutting-edge basic and/or translational research on the molecular, cellular and neurobiological mechanisms of psychiatric disorders, especially in relation to risk genes for schizophrenia and bipolar disorder, synapse development/elimination, synaptic function/plasticity, neuron-glia interactions, and neural circuitry/interneurons. . Sheng laboratory focuses on mechanisms regulating axonal transport that is essential for the maintenance of synaptic function and axonal homeostasis. Is this useful? The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Following postdoctoral research in the lab of Lily Jan at the University of California, San Francisco, Sheng served as a faculty member in the Department of Neurobiology . Postdoctoral Associate - Sheng Lab Broad Institute of MIT and Harvard Cambridge, MA 1 month ago Be among the first 25 applicants Director, Cornell Institute of BiotechnologyDirector, Center for Life Science Enterprise. Senior investigator, Chief of Synaptic Functions Section, NINDS, NIH. Eunah Yu received her PhD in Neuroscience from Seoul National University. Lawrence Berkeley National Laboratory (LBNL), commonly referred to as the Berkeley Lab, is a United States national laboratory owned by, and conducting scientific research on behalf of, the United States Department of Energy.Located in the hills of Berkeley, California, the lab overlooks the campus of the University of California, Berkeley, and is managed by the University of California system. 617-714-7021. Shengs molecular studies of the structure and function of synapses (the communication junctions between brain cells) while at MGH and MIT have enhanced our understanding of the neural basis of cognitive function and dysfunction, including learning and memory, neurodevelopmental disorders, and dementia. Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broads Stanley Center for Psychiatric Research. Pasadena, CA 91125. The trainees in core faculty labs are typically engaged in one or more of the Broad programs, and often benefit from and collaborate with the Broad platforms. He is also a professor of neuroscience in MIT's Department of Brain and Cognitive Sciences, and an . Current Youth Development Coordinator at David Scott School - Brotherhood of St Laurence, responsible for developing and creating industry immersion events with the desire of expanding students' future horizons by facilitating career development programs and providing vocational guidance for senior (Year12) students in the preparation for post-school transition. All Companies Boston University (6) Brigham & Women's Hospital(BWH) (3) Northeastern University (2) Veeva (2) University of Massachusetts Medical School (2) Veeva Systems (2) Dana-Farber Cancer Institute (2) Berklee College of Music, Incorporated (1) The Broad Institute, Inc. (1) Mitsubishi Electric Research Laboratories (1) Suffolk University (1) Broad Institute (1) Boston Conservatory at . Maybe. Software Engineer. Gladstone is dedicated to mentoring tomorrow's leaders and equipping our trainees with a broad set of skills, so they can effect change to improve our world. Shengs molecular studies of the structure and function of synapses (the communication junctions between brain cells) while at MGH and MIT have enhanced our understanding of the neural basis of cognitive function and dysfunction, including learning and memory, neurodevelopmental disorders, and dementia. We are seeking a motivated Computational Associate II (CA) to join the Sheng Lab at the Broad Institute of MIT and Harvard. We are at a critical point where genetic and biological insights are emerging that can transform the way we study, diagnose, and treat mental illness. Job Description The Broad Institute of MIT & Harvard is looking for outstanding postdoctoral scholars to join the laboratory of Morgan Sheng, Co-Director of the Stanley Center for Psychiatric Research, The mission of the Stanley Center is to improve the lives of patients suffering from serious mental illnesses, through groundbreaking basic and translational research. Through programs spanning genetics, biology, and therapeutic development, Broad researchers are making discoveries that drive biomedical science forward. 3 Broad Institute of MIT and . Biological products exc.diagnostic Umbilical cord blood stem cells and collection, storage, should be the technical services and research and development) Sheng Tai. The research of her group focuses on translating emerging genetics into biology and to enable next-generation . Meet our members, staff scientists, fellows and other Broadies. 30 The Broad Institute Postdoctoral Chemistry jobs in Us. From 2008 to 2019, Sheng was Vice-President of Neuroscience at Genentech, a leading biotech company, where he led research and drug discovery efforts for major diseases of the nervous system. His Ph.D. thesis was completed at Harvard Medical School in the lab of Michael Greenberg. Additionally, developing new . Currently, the Sheng lab focuses on three areas of research: Immune response to infection and vaccination: We develop computational methods to study immune responses . Email. . Published by at July 3, 2022. Micro-Star International Co., Ltd. (LEI# 254900F4E0BDGJSSD870) is a legal entity registered with Bloomberg Finance L.P.. Much of the oral arguments centered on legal standing, which is the right of a party to bring a lawsuit to court.In the first case, Biden v. Nebraska, several justices questioned whether Missouri one of six states suing had the right to bring a case on behalf of Mohela, an independent state-created student loan servicer. Job Description. 415 Main St. Shawn.Sheng@nrel.gov 303-384-7106 . As Co-Director of the Stanley Center, Sheng will work with Stanley Center Director Steven Hyman to shape the centers scientific vision and direction, in addition to overseeing the centers therapeutic efforts, in conjunction with the Broads Center for the Development of Therapeutics. More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research. Get alerts to jobs like this, to your inbox. The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Combining cutting-edge technologies from structural biophysics, molecular engineering, and translational . Visit our free public educational space that showcases how researchers at the Broad and their colleagues around the world seek to understand and treat human disease. It requires basic molecular biology expertise and laboratory equipment, including . The scope will include integration with other internal and external genomics datasets. Get notified about new Research Scientist jobs in United States. Following postdoctoral research in the lab of Lily Jan at the University of California, San Francisco, Sheng served as a faculty member in the Department of Neurobiology at Massachusetts General Hospital and Harvard Medical School (1994-2001) before joining MIT (2001-2008). Using genetic mouse models, his group is addressing several fundamental questions: (1) how mitochondrial transport is regulated to sense changes in synaptic activity, mitochondrial integrity, axon injury and pathological stress; (2) how neurons coordinate late endocytic transport and autophagy-lysosomal function to maintain cellular homeostasis and distal degradation capacity; (3) how impaired transport contributes to synaptic dysfunction and axonal pathology in neurodegenerative diseases. During his Ph.D., he . The Xpert HIV-1 qualitative assay (Xpert HIV-1 Qual; Cepheid, Sunnyvale, CA, USA) for early infant diagnosis is considered to be a point-of-care test according to the REASSURED criteria; 9 although it takes 90 min, the assay is able to provide results on the same day as testing. Phone. Frequently searched careers. 910: 2001: PDZ domains: structural modules for protein complex assembly. Journal of Biological Chemistry 277 (8), 5699-5702, 2002. Sheng received a B.A. 699 Bradley C. Paasch, Reza Sohrabi, Kinya Nomura & Sheng Yang He 700 701 . His Ph.D. thesis was completed at Harvard Medical School in the lab of Michael Greenberg. Website. Since we are not allowed to take photos so only the photo from the outside is attached. 1. Neuron 29 (2), 353-366, 2001. A multimodal molecular cell-type atlas of the MOp. See popular questions & answers about Broad Institute; Post-Doctoral Associate - Neuroscience Department. Compositions and Methods for Conversion of Aldehydes to Alkanes (2011) Weiqing Zeng and Sheng Yang He. in chemistry with honors from Caltech in 1999, and a . Structural Insights of Non-canonical U-U Pair and Hoogsteen Interaction Probed with Se Atom. A physician and a scientist, Morgan Shengis author of more than 200 peer-reviewed publications focused on the molecular cellular biology of synapses and synaptic plasticity, and pathogenic mechanisms of neurodegenerative diseases. Learn about our mission, leadership, history, and partner institutions. Postdoctoral Associate - Sheng Lab in The Broad Institute, Inc. Cambridge, MA. EEO is The Law - click here for more information, Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled. Shawn has a broad range of experience: mechanical and electrical system modeling and analysis; data sensing and sensor placement; signal processing; machine learning and artificial intelligence; machine defect classification and level evaluation; machine life prognosis; multi scale modeling; traditional and . LinkedIn profile Steven Hyman, M.D. gu_hongcang@hotmail.com. He is also a professor of neuroscience in MITs Department of Brain and Cognitive Sciences, and an affiliate of both the McGovern Institute for Brain Research and the Picower Institute for Learning and Memory. TJ is an Instuctor in Dr. Ben Neale and Morgan Sheng's groups. Research Areas . The P4 lab is located in a new developing zone about one hour car ride from the current institute location in central Wuhan city. Just another site. Epub 2017 Dec 1. Review. Dr. Fei Chen, a current Broad fellow and co-inventor of expansion microscopy, is building a lab at the Broad Institute that is focused on developing methods for studying differences in genome structure and mRNA expression. . This job is no longer available, but here are similar jobs you might like. We join with institutions and scientists the world over to address foundational challenges in science and health. becky ending explained. Dr. Sheng received the 2021 Dr. Francisco S. Sy Award for Excellence in Mentorship at HHS. Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broad's Stanley Center for Psychiatric Research. Full-Time. NE30-6031. All Rights Reserved. Jiaoti Huang, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave., 13-229 CHS . 2012 - 2017 Ershela Durresi, Ph.D. Medical Student, Harvard Medical School . All Broad employees, regardless of work location, must be fully vaccinated for COVID-19 by Tuesday, October 12, 2021. In 1990, he earned his Ph.D. in molecular genetics from Harvard University and completed his postdoctoral fellowship at the University of California, San Francisco. Blainey Lab Golub Lab Hung Lab Lander Lab Liu Lab Regev Lab Schreiber Lab Sellers Lab Xavier Lab Zhang Lab Institute Member labs Eric Alm, MIT Paola Arlotta, Harvard Picower Professor of Biology and Neuroscience; Director, RIKEN-MIT Laboratory for Neural Circuit Genetics. In November 2022, Broads Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th. The Stanley Center has gained unprecedented insight into the genetic basis of psychiatric illness (schizophrenia, bipolar disorder, autism). Explore the connection between art and science and how we bring together artists and Broad scientists through our artist-in-residence program, gallery exhibitions, and ongoing public conversations. This center is developing new paradigms and technologies to scale the discovery of biological mechanisms of common, complex diseases, by facilitating close collaborations between the Broad Institute and the Danish research community. Broad Genomics Platform sequences a whole human genome every four minutes. From 2008 to 2019, Sheng was vice-president of neuroscience at Genentech, a leading biotech company, where he led research and drug discovery efforts for major diseases of the nervous system. A past recipient of the Fondation Ipsen Prize in Neuronal Plasticity and the Young Investigator Award of the Society for Neuroscience, Sheng is author of more than 200 peer-reviewed publications focused on the molecular mechanisms underlying the structure and plasticity of synapses and the molecular-cell biology of neurodegeneration. Broad brings people together to advance the understanding and treatment of disease. Millions of years of co-evolution between plants and microbes have resulted in an intricate web of attack, counter-attack, decoy, and hijacking mechanisms in biology. Borislav Dejanovic, PhD (Staff Scientist/ Group Leader, Broad Institute), Sarah Wade (Research Associate, Broad Institute), Core Institute Member, Broad Institute of MIT and Harvard, Co-Director of the Stanley Center for Psychiatric Research at the Broad Institute, Office: Broad Institute, 75 Ames St. Room 9023. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery. The Stanley Center aims to reduce the burden of serious mental illness by contributing new insights into pathogenesis, identifying biomarkers, and paving the way toward new treatments. About the Lab. Published in NANO Letters, the study was led by Zhi Sheng and Deborah . Dr. Shengreceived the2021 Dr. Francisco S. Sy Award for Excellence in Mentorship at HHS. . Yun-Sheng Chen is an assistant professor at the University of Illinois, Urbana-Champaign. As the Director for Translational Neurobiology at Stanley Center, Dr. Pan aspires to translate the understanding of the genetics and biology of psychiatric and neurological illnesses to novel therapeutics for severe mental illnesses. At MIT from 2001 to 2008, he served as professor in the Department of Brain and Cognitive Sciences and the Department of Biology, was a member of the Picower Institute for Learning and Memory, and was a Howard Hughes Medical Institute investigator. Sheng Lin-Gibson is the chief of the Biosystems and Biomaterials Division at the National Institute of Standards and Technology (NIST). Howard Hughes Medical Institute, Duke University, Durham, NC, USA . She leads the ICE-T (ion channel electrophysiology and technology) effort enabled by Broadnext10 initiative to utilize state-of-art technologies for studying ion channels and electrogenic transporters, and to find novel ways to modulate these highly specialized membrane proteins. Her group has expertise in the physiology of ion channels, part of the large protein family critical to neurons firing and muscles moving. 32. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery. The position will provide an opportunity to become a part of the computational biology community at the Broad Institute. Sheng is a fellow of the Royal Society (UK), a fellow of the Academy of Medical Sciences (UK), a fellow of the American Association for the Advancement of Science, and honorary fellow of Corpus Christi College, Oxford. Morgan Sheng, a neurobiologist and physician-scientist with deep experience in both basic research and drug discovery, has joined the Broad Institute of MIT and Harvard as its newest Core Member and as Co-Director of the institute's Stanley Center for Psychiatric Research. From Lab to Real Life: How A*STAR supported a scientist's entrepreneurial journey. Eightformer trainees were appointed with faculty positions in an academic setting. We work closely with pharmaceutical, biotech, and technology partners to accelerate the translation of our discoveries. Find our contact information, directions to our buildings, and directory. - Cambridge, MA 02139-4307 |(617) 253-5748, For Emergencies|Accessibility|Adapting to COVID, A physician and a scientist, Morgan Sheng. Sheng-Yong NIU | Cited by 405 | of Broad Institute of MIT and Harvard, MA | Read 19 publications | Contact Sheng-Yong NIU Fei Chen, Principal Investigator. All Broad employees, regardless of work location, must be fully vaccinated for COVID-19 by Tuesday, October 12, 2021. Geplaatst op 3 juli 2022 door Analyze large RNA-Seq datasets to profile transcriptomes from different brain regions at different ages and interpret results to derive important biological insights into these models. This candidate will collaborate with biologists and geneticists to perform various analysis including transcriptomics and proteomics analysis, pathway analysis and biological interpretations. This center is developing new paradigms and technologies to scale the discovery of biological mechanisms of common, complex diseases, by facilitating close collaborations between the Broad Institute and the Danish research community. - Investigating stem cells, regeneration and ageing using Planarian flatworms. 69, Lide St. Zhonghe Dist., New Taipei City, TW. Neumar RW, Nolan JP, Adrie C, et al. Ringel, Alison E. . Chemical biology and therapeutics science, Genome regulation, cellular circuitry, and epigenomics, Merkin Institute for Transformative Technologies in Healthcare, Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Several pre-existing RSV lineages powered the 2022 surge, Blood stem cells are susceptible to ferroptosis, a type of cell death, Rare genetic variants can reveal much about disease biology, Researchers map brain cell changes in Alzheimers disease. Merkin Building More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research.